ARCHITECTURE

EFFECT OF FACTORY LAYOUT ON ORGANIZATIONAL SAFETY PROGRAMMES

Abstract Factory layout of any industry must be effective in flow of workers and material. This is necessary for a smooth manufacturing process. Factory layout is effective if the output from the layout is realized at a minimum possible cost with little or no industrial accident. In this study, an assessment was carried out on …

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A STUDY OF THE PHARMACOLOGICAL EFFECTS OF METHANOL EXTRACT OF RIPE AND UNRIPE PLANTAIN

INTRODUCTION Musa paradisiaca Linn. (Plantain) is an evergreen plant with an aerial pseudostem, an underground rhizome and a height of 2 to 9 m (Ekunwe and Ajayi, 2010). The leaves are oblong, deep green and narrowed to the base (Iman and Akter, 2011). The fruits are edible, contain about 220 Calories and are traditionally used …

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EVALUATION OF THE CHOLINERGIC EFFECTS OF BDF – 8503 ON THE GUINEA PIG ILEUM

Introduction Imidazoline binding sites (IBs) are widelydistributed in the central (CNS) and peripheral nervous systems (PNS) of mammaliancells.1 Three IB sub types have been proposed:I1, I2, I3.2-4Among them, only I1subtype has been effectively characterized.5I2-IB sub type,originally described as the Imidazoline-Guanidinium Receptive Site (IGRS) and characterized by idazoxan binding,6has been identified as allosteric binding site on …

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EVALUATION OF POSSIBLE CHOLINERGIC (VAGAL) EFFECTS OF THE ANTI-HYPERTENSIVE DRUGS – PRAZOSIN AND ATENOLOL IN HEALTHY MALE VOLUNTEERS

In a prospective, randomized, double-blind, cross-over, placebo-controlled study (The GENRES Study), 208 moderately hypertensive Finnish men (aged 35 to 60 years) were treated for 4 weeks with antihypertensive drugs from four different classes: amlodipine (5 mg), bisoprolol (5 mg), hydrochlorothiazide (25 mg), or losartan (50 mg) daily. Each individual received each of the four monotherapies …

EVALUATION OF POSSIBLE CHOLINERGIC (VAGAL) EFFECTS OF THE ANTI-HYPERTENSIVE DRUGS – PRAZOSIN AND ATENOLOL IN HEALTHY MALE VOLUNTEERS Read More »

EFFECTS OF KARGASOK TEA ON BLOOD PRESSURE OF NORMOTENSIVE MAN

Recently BP measurement was added to the regular check-up at high schools and universities in Japan, and the results of this initiative indicated that up to 20% of young subjects have elevated BP (2,3). Follow-up studies have suggested that BP elevation at the school check-up is closely associated with the onset of EH and/or EH-related …

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A STUDY OF MECHANISM FOR NICOTINE TACHYPHYLAXIS ON GUINEA PIG ILEUM.EFFECT OF CYCLOSPORINE-A ON VARIOUS FORMS OF INFLAMMATION IN RATS

Introduction Honey is a sweet and flavorful natural product of honey bees that is derived from floral nectars and other plant secretions [1]. The major component of honey is a complex mixture of sugars such as glucose, fructose and sucrose with small number of other constituents including minerals, amino acids, proteins, enzymes, organic acids, phenolic …

A STUDY OF MECHANISM FOR NICOTINE TACHYPHYLAXIS ON GUINEA PIG ILEUM.EFFECT OF CYCLOSPORINE-A ON VARIOUS FORMS OF INFLAMMATION IN RATS Read More »

A COMPARISON OF THE EFFECTS OF INTRADERMAL CHLOROQUINE AND HISTAMINE IN HEALTHY BLACK SUBJECTS

Background: Chloroquine (CQ) is a prototypical systemic and intradermal pruritogen for histamine-independent (nonhistaminergic) itch in mice and humans. The predictive validity of this model is poorly documented in dogs. Hypothesis/objective: To determine pruritogenic and inflammatory effects of systemic and i.d. CQ injections in healthy dogs. Animals: Ten healthy purpose-bred laboratory beagles. Methods and materials: All …

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THE EFFECTS OF WATER EXTRACT OF TELFAIRIA OCCIDENTALIS ON THE GUINEA PIG ILEUMEFFECTS OF HISTAMINE, ADRENALINE AND ACETYLCHOLINE ON RAT ISOLATED DETRUBOR MUSCLE

1. Introduction The overactive bladder (OAB) is a symptomatic diagnosis based on the presence of urgency, with or without incontinence, and is usually accompanied by frequency and nocturia [1]. Its presence imposes a huge burden on the healthcare system, society, and affected individuals [2]. Patients with OAB symptoms and detrusor overactivity (DO) can be divided …

THE EFFECTS OF WATER EXTRACT OF TELFAIRIA OCCIDENTALIS ON THE GUINEA PIG ILEUMEFFECTS OF HISTAMINE, ADRENALINE AND ACETYLCHOLINE ON RAT ISOLATED DETRUBOR MUSCLE Read More »

EVALUATION OF A LOCAL ELECTROSHOCK CONVULSION MODEL FOR SCREENING POTENTIAL ANTI-EPILEPTIC DRUGS

INTRODUCTION In spite of the currently available therapeutic arsenal of old and newantiepileptic drugs (AEDs), almost one-third of epileptic patients continue to present seizures that appear to be refractory to all phar-macological schemes (1, 2). Subsequently, there is a substantial need to develop new and more effective AEDs, and numerous com-pounds are now in preclinical …

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SCREENING OF A NEW DRUG BDF 8503 FOR ANY ANTIHISTAMINIC EFFECT: COMPARISON OF THE PA2 OF A KNOWN HISTAMINE RECEPTOR ANTAGONIST, MEPYRAMINE, WITH THAT OF BDF 8503

INTRODUCTION The prevalence of allergic diseases (asthma, allergic rhinitis, atopic dermatitis etc.) has been rapidly growing. The goal of treatment of these conditions represents a blocking effect of histamine release from basophils and mast cells and is considered to be the key cause of all the symptoms associated with allergic inflammatory response. Antihistamines are drugs …

SCREENING OF A NEW DRUG BDF 8503 FOR ANY ANTIHISTAMINIC EFFECT: COMPARISON OF THE PA2 OF A KNOWN HISTAMINE RECEPTOR ANTAGONIST, MEPYRAMINE, WITH THAT OF BDF 8503 Read More »

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